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Symptoms of paget disease of breast cancer

Symptoms of paget disease of breast cancer

This is the most important less common part of cancer. In this topic we know about Symptoms of Paget Disease Of Breast Cancer.

  • A lump in the breast
  • Thickening skin on the breast
  • Inwarded nipple
  • Bloody nipple discharge
  • Redness and itching on the breast
  • Breast skin looks like orange peels
  • Shown eczema like on the nipple and areola both
  • Scaly skin on the nipple

Cause of paget disease of breast cancer

Paget disease of breast cancer is the most widely accepted theory is that the disease results from an underlying ductal breast cancer when cancer cell travel through milk dust to the nipple.

This cells are the original tumor cells. That spread around the nipple. An another theory is about paget disease can develop independently in the nipple.

Test and treatment

  1. Biopsy

   a. Surface biopsy

   b. Shave biopsy

   c. Punch biopsy

   d. Wedge biopsy

   e. Removing nipple

  1. Imaging test

a. Mammogram

b.Breast MRI

c. Breast ultrasound

  1. Mastectomy
  2. Lumpectomy
  3. Radiation therapy
  4. Chemo therapy
  5. Hormonal therapy

a. Hormone receptor ( HR ) test

b. Selective estrogen receptor modulator ( SERM )

c. Aromatase inhibitor ( AI )

Symptoms Of Angio Sarcoma / Cause / Treatment

Symptoms Of Angio Sarcoma

This is the most important less common part of cancer. In this topic we know about Symptoms Of Angio Sarcoma.

  • A lesion that may bleed when seratched or bumped.
    • Swelling in the surrounding skin of breast.
    • A raised, purplish area of skin that looks like a bruise.
    • A bruise-like lesion that grows larger over time.

Cause Of Angio Sarcoma

  As doctors says due to any injury or injury incident, the calls start breaking and extra volume increase around the nipple and areola.

The mutation tells the cell to grow quickly, making more abnormal cells. The abnormal cells continue living when other cells would die.

Test and treatment

  1. Surgery
  2. Radiation therapy

2.1 High energy beams

2.2 X-rays

  1. Chemo therapy

Symptoms Of Metastatic Breast Cancer (MBC)

Symptoms Of Metastatic Breast Cancer (MBC)

This is the next types of breast cancer. In this topic we know about Symptoms Of Metastatic Breast Cancer (MBC).

  • It the cancer has spread to the liver, symptoms may include nausea, fatigue, swelling of the feet and hands or yellowing skin.
  •  It the breast or chest wall is affected, symptoms may include pain, nipple discharge, or lump or thickening in the breast or armpit.
  • If the cancer has spread to the lungs, symptoms may include coughing, chest pain or fatigue and shortness of breath.
  • If the cancer has spread to the central nervous system, which includes the brain or spinal cord, symptoms may include pain, memory loss double vision or blurred, headache.
  • It the cancer has spread to bones, symptoms may include pain, fractures due to high calcium levels.

Cause Of Symptoms Of Metastatic Breast Cancer

As we know metastatic bread cancer is a 4th stage of cancer,  that has spread to another past of the body , most commonly the liver, brain, bones or lungs. Nearly  30% of women diagnosed with early stage breast cancer can develop metastatic disease.

The main reason for metastatic breast cancer is when the cancer cells separate from their original tumor and reach different part of the body through the bloodstream or lymph system.

Test And Treatment

  1. Surgery
  • Cryoablation
  1. Chemotherapy
  • CAF/FAC
  • FEC
  • AC
  • EC
  • CMF
  • Docetaxel
  • GT
  • Gemcitabine
  • Paclitaxel
  1. Radiation Therapy
  1. Hormonal Therapy
  1. Targeted Therapy
  • Afinitor
  • Avastin
  • Enhertu
  • Herceptin
  • Ibrance
  • Kadcyla
  • Kisqali
  • Lynparza
  • perjeta
  • Tykerb
  • Verzenio
  1. Local treatments for distant areas of metastasis
  1. Genetic testing
  1. Complementary and holistic medicine
  1. Clinical Trials

Symptoms Of Invasive Ductal Carcinoma (IDC)

Symptoms Of Invasive Ductal Carcinoma (IDC)

In this topic we know about Symptoms Of Invasive Ductal Carcinoma (IDC) / Invasive lobular carcinoma (ILC).

  • Nipple pain or the nipple turning inward .
  • Nipple discharge.
  • Lump in the breast.
  • Thickening of the breast skin.
  • Rash and redness of the breast.
  • Dimpling around on the breast areola.
  • Swelling in one breast.
  • Lumps in the armpit.

Cause Of Symptoms Of Invasive Ductal Carcinoma

The reason for this is not very clean, but researches believe that believe that uncontrolled growth of milk producing cells is one of the reasons.

The result is accumulation of excess cells that can from a mass, or tumor and potentially spread to nearby lymph nodes and apart areas of the body.

The fundamental reason for those cellular changes, However, remains unclear.

Test and Treatment

  1. Surgery
  1. Chemo therapy
  • Adjuvant therapy
  • Neo adjuvant therapy
  1. Radiation therapy
  • External bean radiation
  • Internal partial – breast irradiation or Brachy Therapy
  • External partial – breast irradiation
  1. Hormonal therapy / anti estrogen therapy
  • Selective estrogen – receptor response modulators (SERMS)
  • Aromotase inhibitor
  • Estrogen – receptor down regulators (ERDS)
  • Ovarian shutdown or removal
  1. Targeted therapy
  • HER 2 inhibitors drug
  • PARP inhibitors drug
  • DCK 4/6 inhibitors drug
  • PI3K inhibitors drug
  • Herceptin
  • Kadcyla
  • Nerlynx
  • Perjeta
  • Afinitor
  • Enhertu
  • Ibrance
  • Kisqali
  • Lynparza
  • Piqray
  • Talzenna
  • Tykerb
  • Verzenio